Cole-Parmer CG-500 Freezer/Mill®

Product Description

The comminution and homogenisation of soft, flexible or heat-sensitive materials is often a problem in the laboratory. Many samples such as polymers, food, biological samples or active pharmaceutical ingredients cannot be comminuted conventionally at room temperature due to their consistency or heat sensitivity.

The grinding principle is as ingenious as it is simple – the grinding container, which is fitted with the sample and a rod-shaped, magnetisable grinding tool and sealed with magnetisable end caps, is inserted into a holder in the mill, which is enclosed by two magnetic coils. During the entire grinding process, everything is immersed in liquid nitrogen, which is located in the lower, very well insulated part of the mill. This ensures the cooling and embrittlement of a sample previously introduced at room temperature as well as the permanent cooling of the material to be ground during the grinding process. Grinding is carried out continuously at a constantly low temperature (-196°C), whereby the sample itself does not come into direct contact with the liquid nitrogen and is therefore free of contamination.

A complete grinding programme consists of several sections and cycles, all grinding parameters (pre-cooling time, grinding time per cycle, holding time, number of grinding cycles, grinding speed) are simply entered via an LCD touchscreen. They can be stored as retrievable grinding programmes and run automatically when the respective programme is started. This enables short set-up times and reproducible grinding results.

During the actual grinding process, only the grinding tool inside the grinding container is moved back and forth in a magnetic field, crushing the sample material at both ends of the container. There is no mechanical stress on the grinder and therefore hardly any wear. If the lid of the grinder is opened while grinding is in progress, the grinder switches off immediately via appropriate safety devices. The grinder also switches off if the liquid nitrogen level drops too low.
The Cole-Parmer CG-500 Freezer/Mill® is supplied with an auto-fill system as standard and can therefore be connected directly to a suitable nitrogen container. If required, liquid nitrogen is automatically supplied from the nitrogen tank via a supply line and a corresponding valve circuit when the internal fill level in the mill is queried, thus preventing the fill level from being too low and the mill from being switched off. However, manual filling with liquid nitrogen is also possible if no suitable nitrogen container is available or a permanent connection to the mill is not necessary (e.g. low sample volume) or desired. The filling mode is selected via the LCD touchscreen.
The grinder has two grinding chambers and holds up to 2 x 4 of the available small grinding vessels with a capacity of 0.1 to 5 g each (insert with adapter), 2 x 4 times three micro grinding vessels of the micro grinding set with a capacity of 3 x 0.1 to 0.5 g each (insert via adapter) or two grinding vessels each of the medium (grinding capacity 2 x 1 to 40 g) and large grinding sets (grinding capacity 2 x 1 to 100 g). Above the actual grinding container holder, the two grinding chambers, there are two further chambers in each case, in which already prepared grinding vessels can be stored and thus pre-cooled
The Cole-Parmer CG-500 Freezer/Mill® cryogenic mill is often seen as the last alternative for sample preparation when all else fails…

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Die Kryomühlen von Cole-ParmerFreezer/Mill® Cryogenic Grinders

Specifications

Grinding capacity: 2 x 0.1 to 100 g

Controls: Touchscreen

Grinding principle: Electromagnet-driven steel impactor

Liquid nitrogen consumption: 20 to 25 litres for pre-cooling and initial filling

6 to 8 litres per hour during operation

Mains connection: 230 V / 50 Hz

Dimensions: 64.8 cm height x 50.8 cm width x 53.3 cm depth

Weight: 35.4 kg

Options and Accessories

• Micro-grinding set comprising three individual grinding jars with a grinding capacity of 0.1 to 0.5 g, made from a combination of polycarbonate and magnetic steel (not stainless)

• Various grinding vessels with a grinding capacity of 0.1 to 5 g in the following material combinations:

• Polycarbonate / magnetic steel (non-stainless)

• Polycarbonate / chrome-free steel (non-stainless)

• All-polycarbonate (with grinding tool encapsulated in polycarbonate), completely metal-free

• Stainless steel / magnetic steel, completely polymer-free

Various grinding vessels with a grinding capacity of 1 to 40 g in the following material combinations:

• Polycarbonate / magnetic steel (non-stainless)

• Polycarbonate / chromium-free steel (non-stainless)

• Polycarbonate throughout (with grinding tool encapsulated in polycarbonate), completely metal-free

Various grinding jars with a grinding capacity of 1 to 100 g in the following material combinations:

• Polycarbonate / magnetic steel (non-stainless)

• Polycarbonate / chromium-free steel (non-stainless)

• Stainless steel / magnetic steel, completely polymer-free

Various opening tools and adapters for grinding containers

Applications